Mycobacterium Tuberculosis Nucleic Acidum et Rifampicin Repugnantiae
Product nomen
HWTS-RT074B-Mycobacterium Tuberculosis Acidum nuclei et Rifampicin Repugnantia Detection Kit (Curve liquefaciens)
Testimonium
CE
Epidemiologia
Mycobacterium tuberculosis ， mox ut Tuberculus bacillus , TB est bacterium pathogenicum quod tuberculosis causat.In statu, vulgo adhibita prima linea anti-tuberculosis medicamenta includunt isoniazid, rifampicin et hexambutolum, etc. Secunda linea anti-tuberculosis medicamenta includunt fluoroquinolones, amikacin et kanamycin, etc. Nova medicamenta evoluta sunt linezolida, bedaquilina et delamani, etc. Attamen, ex falso usu medicamentorum tuberculosis anti- quorum indolem structurae muri cellae mycobacterium tuberculosis, mycobacterium tuberculosis pharmaca resistentia in medicamentis anti-tuberculosis, quae graves provocationes ad praeventionis et curationem tuberculosis affert.
Rifampicin late in curatione tuberculosis pulmonis ab annis 1970 aegris pulmonalis usus est et effectum notabilem habet.Prima optio chemotherapylem tuberculosis pulmonis aegros minuendi fuit.Repugnantia rifampicin maxime fit per mutationem gene rpoB.Etsi nova medicamenta anti-tuberculosis constanter egrediuntur, et efficacia clinica pulmonis tuberculosis aegri etiam emendare perseverunt, adhuc defectus relativus anti-tuberculosis medicamentis et phaenomenon medicamentorum irrationalium in usu clinico relative altum est.Patet, Mycobacterium tuberculosis in patientibus tuberculosis pulmonis non potest omnino necari opportune modo, quae tandem ad varios gradus resistentiae medicamentorum in corpore aegri ducit, cursum morbi prolongat et periculum mortis aegri auget.
Channel
| Channel | Canales et Fluorophores | Reactionem Buffer A | Reactionem Buffer B * | Reactionem Buffer C |
| FAM Channel | Notario: FAM, Quencher: None | rpoB 507-514 | rpoB 513-520 | 38KD et IS6110 |
| CY5 Channel | Notario: CY5, Quencher: None | rpoB 520-527 | rpoB 527-533 | / |
| HEX (VIC) Channel | Notarius: HEX (VIC), Quencher: Nullus | Internum imperium | Internum imperium | Internum imperium |
Technical Parameters
| Repono | ≤-18℃ in tenebris |
| Fasciae vita | XII mensibus |
| Specimen Type | Sputum |
| CV | ≤5.0% |
| LoD | mycobacterium tuberculosis 50 bacteria/mL rifampicin repugnans ferox genus: 2x103Bacteria/mL* homozygous mutant: 2x103Bacteria/mL* |
| Specification | Genus mycobacterium tuberculosis silvestris detegit ac situs mutationis genesis aliorum medicamentorum resistentiae sicut katG 315G>C\A, InhA-15C> T, eventus experimentum nullam repugnantiam praebent rifampicin, quae significat nullum reactivitatem crucis. |
| Instrumenta applicabilia: | SLAN-96P Real-time PCR Systems BioRad CFX96 Real-time PCR System LightCycler480® Real-time PCR System |
Opus O
Si Macrone & Micro-teste Generali DNA/RNA Ornamento uteris (HWTS-3019-50, HWTS-3019-32, HWTS-3019-48, HWTS-3019-96) (quod adhiberi potest cum Macrone & Micro-test Automatic Acidum nucleicum Extractor (HWTS-3006C, HWTS-3006B)) vel Macro & Micro-test Viralis DNA/RNA Columna (HWTS-3022-50) by Jiangsu Macro & Micro-Test Med-Tech Co., Ltd. 200μL Imperii positivi, imperium negativum et sputum processit specimen in ordine probandum, et adde 10μL imperium internum separatim in Imperium positivum, imperium negativum et sputum processit ut probetur, et gradus subsequentes stricte exerceantur. iuxta mandatum extractionem.Extractum specimen voluminis 200μL est, et volumen elutionis commendatum 100μL est.
