Humanum BCR-ABL FUSIO Gene Mutationem
Product Name
HWTS-Ge010a-Humanum BCR-ABL FUSIO FUSIO Gene Mutationem Deprehensio Kit (Fluorence PCR)
HWTS, Ge016a-Frigidus-exaruit Humanum BCR-ABL Fusion Gene Mutationem Deprehenter Kit (Fluorence PCR)
Epidemiology
Longos myelogenousleukemia (CML) est maligna clonal morbo hematopoietic caule cellulis. Plus quam XCV% of CML aegris portare Philadelphia chromosoma (PH) in sanguine cellulis. Pradominant Pathogenesis de CML est ut sequitur: et BCR-ABL eget gene formatae per translocacum inter ABL proto-oncogene (Abason Murine Leukemia virales Homolog I) in longum brachium de chromosomis IX (9Q34) et breakpoint botter regione BCR) gene in tempore brachium chromosomatum XXII (22Q11); Fusion protein encoded per hoc gene has tyrosine kinase (tk) operatio, et operatur ejus downstream signaling meatus (ut ras, pi3k et inhibere cellula apoptosis, faciens cellulis et inhibere inhibere cellula, faciens cellulis et inhibere et inhibere cellulis, et inhibere cellulis et inhibere, et inhibere cellulis et inhibere et inhibere cellulis, et inhibere et inhibere cellulis, et inhibere cellulis et inhibere, et ita causing Eventum CML. BCR-ABL est unus de magna Diagnostic Indicatores CML. In dynamic mutatio ejus transcript gradu est certa indicator prognostica judicium Leukemia et potest ad praedicere recursu Leukemia post curatio.
Channel
| Fam | Bcr-ABL FUSIO Gene |
| Vic / Hex | Internum |
Technical parametri
| Repono | Liquid: ≤, XVIII ℃ in tenebris |
| PLUTEUM-vitae | Liquid: IX mensibus |
| Specimen Type | Os medulli samples |
| LOD | M III / ml |
| Specifica
| Non est crucem-reactivity cum aliis eget genes Tel-AML1, E2A, PBX1, MLL, AF4, AML1, eto, et PML-Rara |
| COMPRESSUS | Applicari Biosystems (VII) D Real-vicis PCR Systems Applicari Biosystems (VII) D ieiunium realis-vicis PCR systems QuantStudio® V Real-Time PCR Systems Slan-96P realis-vicis PCR systems LightcyCler®®®® Real-vicis PCR ratio Linenene (IX) DC plus realis-vicis PCR deprehensio ratio MA-(VI) Real-vicis quantitatis scelerisque cycler BIOD CFX96 Real-vicis PCR ratio BIOD CFX Opus XCVI Real-vicis PCR ratio |
