Mycobacterium Tuberculosis INH Resistentia

Description:

Hoc ornamentum adhibetur ad qualitatem gene mutationis amino acidi geneis katG (K315G>C) et gene mutationis promotoris regionis InhA gene (- 15 C>T).


Product Detail

Product Tags

Product Name

HWTS-RT002A-Mycobacterium Tuberculosis Isoniazid Resistentia Detection Kit (Fluorescens PCR)

Testimonium

Suspendisse FDA

Epidemiologia

Isoniazid, clavis anti-tuberculosis pharmacum anno 1952 introductum, unum ex efficacissimis medicamentis ad tractationem activam tuberculosis coniunctam et unum pharmacum ad tuberculosis latentem.

KatG gene principale est descriptam catalasi-peroxidasem et katG gene mutationis synthesim acidi mycolici parietis cellae promovere potest, bacteria isoniazid renitentem facit.Expressio KatG negative connectitur cum mutationibus in INH-MIC, et diminutio 2-triplex in expressione katG resultat paulo ampliore 2-ovili augmento in MIC.Alia causa resistentiae isoniazidorum in mycobacterio tuberculosis occurrit, cum basis insertionis, deletionis vel mutationis occurrit in InhA gene loco mycobacteri tuberculosis.

Channel

ROX inhA (-15C>T) situs·
CY5

katG (315G>C) site

VIC (HEX)

IS6110

Technical Parameters

Repono ≤-18℃ in tenebris
Fasciae vita

XII mensibus

Specimen Type

Sputum

CV ≤5.0%
LoD

1 103Bacteria/mL*

Specification Reactivitas in cruce nulla cum mutationibus situum resistentium quattuor medicamentorum (511, 516, 526 et 531) de rpoB gene extra detectionem range detectionis ornamentum.

Instrumenta applicabilia:

Acta Biosystems (VII)D Real-time PCR Systems

Acta Biosystems (VII)D Fast Verus-Tempus PCR Systems

QuantStudio®5 Real-Time PCR Systems

SLAN-96P Real-time PCR Systems

LightCycler®480 Real-time PCR systema

LineGene 9600 Plus Real-time PCR Detection System

MA-6000 Real-time Quantitatis Thermal Cycler

BioRad CFX96 Real-time PCR System

BioRad CFX Opus 96 Real-time PCR System

Opus O

4697e0586927f02cf6939f68fc30ffc


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